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1

CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation

Bajgain, Pradip, Tawinwung, Supannikar, D’Elia, Lindsey, Sukumaran, Sujita, Watanabe, Norihiro, Hoyos, Valentina, Lulla, Premal, Brenner, Malcolm K., Leen, Ann M., Vera, Juan F.

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2018

Language:

english

File:

PDF, 3.12 MB

english, 2018

2

Oncolytic Adenovirus Armed with BiTE, Cytokine, and Checkpoint Inhibitor Enables CAR T Cells to Control the Growth of Heterogeneous Tumors

Porter, Caroline E., Rosewell Shaw, Amanda, Jung, Youngrock, Yip, Tiffany, Castro, Patricia D., Sandulache, Vlad C., Sikora, Andrew, Gottschalk, Stephen, Ittman, Michael M., Brenner, Malcolm K., Suzuk

Journal:

Molecular Therapy

Year:

2020

File:

PDF, 2.39 MB

2020

3

Lymphokines and interferons: A practical approach: Clemens, M.J., Morris, A.G. and Gearing, A.J.H., v + 376 pp. IRL Press, Oxford, 1987. £22.00, ISBN 1-85221-035-4

Malcolm Brenner

Journal:

Journal of Immunological Methods

Year:

1988

Language:

english

File:

PDF, 70 KB

english, 1988

4

Defining the risks of mesenchymal stromal cell therapy

Prockop, Darwin J., Brenner, Malcolm, Fibbe, Willem E., Horwitz, Edwin, Le Blanc, Katarina, Phinney, Donald G., Simmons, Paul J., Sensebe, Luc, Keating, Armand

Journal:

Year:

2010

Language:

english

File:

PDF, 160 KB

english, 2010

5

Gene Therapy: Socioeconomic and Ethical Issues A Roundtable Discussion

Hillman, Alan L., Brenner, Malcolm K., Caplan, Arthur L., Carey, John, Champey, Yves, Culver, Kenneth W., Drummond, Michael F., Freund, Deborah A., Holmes, Edward W., Kelley, William N., Kolata, Gina,

Journal:

Human Gene Therapy

Year:

1996

Language:

english

File:

PDF, 540 KB

english, 1996

6

Clinical Success of Complex Biological Therapies: Be Careful What You Wish For...

Brenner, Malcolm K

Journal:

Molecular Therapy

Year:

2010

Language:

english

File:

PDF, 182 KB

english, 2010

7

Cancer Gene Therapy by Viral and Non-viral Vectors (Brenner/Cancer Gene Therapy by Viral and Non-viral Vectors) || Cancer Therapy with RNAi Delivered by Non-viral Membrane/Core Nanoparticles

Brenner, Malcolm K., Hung, Mien-Chie

Year:

2014

Language:

english

File:

PDF, 451 KB

english, 2014

8

Seek and You Will Not Find: Ending the Hunt for Replication-Competent Retroviruses during Human Gene Therapy

Heslop, Helen E., Brenner, Malcolm K.

Journal:

Molecular Therapy

Year:

2018

Language:

english

File:

PDF, 195 KB

english, 2018

9

Cord Blood Transplant for Very High Risk Hematologic Malignancies in Children Using Conditioning Without Serotherapy

Onishi, Toshihiro, John, Tami, Aguayo-Hiraldo, Paibel Ixia, Tewari, Priti, Naik, Swati, Omer, Bilal, Hegde, Meena, Ahmed, Nabil, Sasa, Ghadir, Brenner, Malcolm K., Heslop, Helen E., Krance, Robert A.,

Journal:

Biology of Blood and Marrow Transplantation

Year:

2018

Language:

english

File:

PDF, 111 KB

english, 2018

10

Adoptive Cell Therapy for Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia

Lulla, Premal D., Mamonkin, Maksim, Brenner, Malcolm K.

Journal:

The Cancer Journal

Year:

2019

Language:

english

File:

PDF, 263 KB

english, 2019

11

Transfer of EBV-specific CTL to prevent EBV lymphoma post bone marrow transplant

Helen E. Heslop, Margot Perez, Ely Benaim, Richard Rochester, Malcolm K. Brenner, Cliona M. Rooney

Journal:

Journal of Clinical Apheresis

Year:

1999

Language:

english

File:

PDF, 20 KB

english, 1999

12

Selection of human antitumor single-chain Fv antibodies from the B-cell repertoire of patients immunized against autologous neuroblastoma

Claudia Rossig, Jed G. Nuchtern, Malcolm K. Brenner

Journal:

Pediatric Blood & Cancer

Year:

2000

Language:

english

File:

PDF, 122 KB

english, 2000

13

Continuous infusion of interleukin-2 in children with refractory malignancies

Raul C. Ribeiro, Donna Rill, Paula K. Roberson, Wayne L. Furman, Charles B. Pratt, Malcolm Brenner, William M. Crist, Ching-Hon Pui

Journal:

Year:

1993

Language:

english

File:

PDF, 481 KB

english, 1993

14

The role of B cell differentiation factors and specific T cell help in the pathogenesis of primary hypogammaglobulinemia

Malcolm K. Brenner, Margaret E. North, Hakikat R. Chadda, Christine A. Newton, Mirek Malkovsky, A. David B. Webster, John Farrant

Journal:

European Journal of Immunology

Year:

1984

Language:

english

File:

PDF, 797 KB

english, 1984

15

Human clones with natural killer function can activate B cells and secrete B cell differentiation factors

Anna Vyakarnam, Malcolm K. Brenner, Joyce E. Reittie, Clare H. Houker, Peter J. Lachmann

Journal:

European Journal of Immunology

Year:

1985

Language:

english

File:

PDF, 572 KB

english, 1985

16

Human large granular lymphocytes induce immunoglobulin synthesis after bone marrow transplantation

Malcolm K. Brenner, Anna Vyakarnam, Joyce E. Reittie, Jennifer Z. Wimperis, Jean Philippe Grob, A. Victor Hoffbrand, H. Grant Prentice

Journal:

European Journal of Immunology

Year:

1987

Language:

english

File:

PDF, 545 KB

english, 1987

17

Adenoviral gene transfer into dendritic cells efficiently amplifies the immune response to LMP2A antigen: A potential treatment strategy for Epstein-Barr virus–positive Hodgkin's lymphoma

Benedikt Gahn, Fernando Siller-Lopez, Angela D. Pirooz, Eric Yvon, Stephen Gottschalk, Richard Longnecker, Malcolm K. Brenner, Helen E. Heslop, Estuardo Aguilar-Cordova, Cliona M. Rooney

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 156 KB

english, 2001

18

Targeting of GD2-positive tumor cells by human T lymphocytes engineered to express chimeric T-cell receptor genes

Claudia Rossig, Catherine M. Bollard, Jed G. Nuchtern, Durriya A. Merchant, Malcolm K. Brenner

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 241 KB

english, 2001

19

Transfer of humoral immunity against cytomegalovirus proteins following transplantation of T-cell-depleted allogeneic bone marrow from seropositive donors

Donna M. Roy, Malcolm K. Brenner, Derek Cook, R. Ian Duncan, Paul D. Griffiths, Dr. Jane E. Grundy

Journal:

Journal of Medical Virology

Year:

1993

Language:

english

File:

PDF, 797 KB

english, 1993

20

Graft-versus-host reactions and bone-marrow transplantation

Malcolm K. Brenner, Helen E. Heslop

Journal:

Current Opinion in Immunology

Year:

1991

Language:

english

File:

PDF, 771 KB

english, 1991

21

An in vivo propagated human acute myeloid leukemia expressing ABCA3

Kevin Norwood, Rui-Yu Wang, Charlotte Hirschmann-Jax, Michael Andreeff, Malcolm K Brenner, Margaret A Goodell, Gerald G Wulf

Journal:

Leukemia Research

Year:

2004

Language:

english

File:

PDF, 176 KB

english, 2004

22

Children with acute leukemia: A comparison of outcomes from allogeneic blood stem cell and bone marrow transplantation

Yu-Feng Lin, David R. Lairson, Wenyaw Chan, Xianglin L. Du, Kathryn S. Leung, Alana A. Kennedy-Nasser, Caridad A. Martinez, Helen E. Heslop, Malcolm K. Brenner, Robert A. Krance

Journal:

Pediatric Blood & Cancer

Year:

2011

Language:

english

File:

PDF, 180 KB

english, 2011

23

An Inducible Caspase 9 Suicide Gene to Improve the Safety of Mesenchymal Stromal Cell Therapies

Carlos Almeida Ramos, Zahra Asgari, Enli Liu, Eric Yvon, Helen E. Heslop, Clio M. Rooney, Malcolm K. Brenner, Gianpietro Dotti

Journal:

Year:

2010

Language:

english

File:

PDF, 744 KB

english, 2010

24

Adoptive T cell therapy of cancer

Malcolm K Brenner, Helen E Heslop

Journal:

Current Opinion in Immunology

Year:

2010

Language:

english

File:

PDF, 155 KB

english, 2010

25

Psychological Stress Evaluator—Two Tests of a Vocal Measure

Malcolm Brenner, Harvie H. Branscomb, Gary E. Schwartz

Journal:

Psychophysiology

Year:

1979

File:

PDF, 963 KB

1979

26

Complement-Fixing CD45 Monoclonal Antibodies to Facilitate Stem Cell Transplantation in Mouse and Man

MALCOLM K. BRENNER, GERALD G. WULF, DONNA R. RILL, KANG-LI LUO, MARGARET A. GOODELL, ZUYONG MEI, INGRID KUEHNLE, MICHAEL P. BROWN, MARTIN PULÉ, HELEN E. HESLOP, ROBERT A. KRANCE

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 209 KB

2003

27

10.1038/81297

Brenner, Malcolm

Journal:

Nature Medicine

Year:

2000

Language:

english

File:

PDF, 1020 KB

english, 2000

28

10.1038/83270

Horwitz, Edwin M., Prockop, Darwin J., Fitzpatrick, Lorraine A., Koo, Winston W.K., Marx, Jeffrey C., Brenner, Malcolm K.

Journal:

Nature Medicine

Year:

2001

Language:

english

File:

PDF, 427 KB

english, 2001

29

10.1038/83276

Horwitz, Edwin M., Prockop, Darwin J., Fitzpatrick, Lorraine A., Koo, Winston W.K., Marx, Jeffrey C., Brenner, Malcolm K.

Journal:

Nature Medicine

Year:

2001

Language:

english

File:

PDF, 104 KB

english, 2001

30

10.1038/8327

Horwitz, Edwin M., Prockop, Darwin J., Fitzpatrick, Lorraine A., Koo, Winston W.K., Marx, Jeffrey C., Brenner, Malcolm K.

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 34 KB

english, 1999

31

Monitoring glucocorticoid therapy: A pharmacokinetic approach

Hill, Malcolm R, Szefler, Stanley J, Ball, Bruce D, Bartoszek, Maryanne, Brenner, A Manon

Journal:

Clinical Pharmacology & Therapeutics

Year:

1990

Language:

english

File:

PDF, 736 KB

english, 1990

32

The best cytokine for the job

Dilloo, Dagmar, Brenner, Malcolm

Journal:

Nature Medicine

Year:

1997

File:

PDF, 133 KB

1997

33

BMT beats autoimmune disease

Krance, Robert, Brenner, Malcolm

Journal:

Nature Medicine

Year:

1998

File:

PDF, 503 KB

1998

34

T cell receptors and cancer: gain gives pain

Brenner, Malcolm

Journal:

Nature Medicine

Year:

2010

Language:

english

File:

PDF, 458 KB

english, 2010

35

Long–term restoration of immunity against Epstein–Barr virus infection by adoptive transfer of gene–modified virus–specific T lymphocytes

Heslop, Helen E., Ng, Catherine Y.C., Li, Congfen, Smith, Colton A., Loftin, Susan K., Krance, Robert A., Brenner, Malcolm K., Rooney, Cliona M.

Journal:

Nature Medicine

Year:

1996

File:

PDF, 973 KB

1996

36

Placental blood transplant: Who will benefit?

Brenner, Malcolm

Journal:

Nature Medicine

Year:

1996

File:

PDF, 253 KB

1996

37

Combined chemokine and cytokine gene transfer enhances antitumor immunity

Dilloo, Dagmar, Bacon, Kevin, Holden, William, Zhong, Wanyun, Burdach, Stefan, Zlotnik, Albert, Brenner, Malcolm

Journal:

Nature Medicine

Year:

1996

File:

PDF, 777 KB

1996

38

Transgenic expression of CD40L and interleukin-2 induces an autologous antitumor immune response in patients with non-Hodgkin's lymphoma

Takahashi, Satoshi, Yotnda, Patricia, Rousseau, Raphael F, Mei, Zhuyong, Smith, Susan, Rill, Donna, Younes, Anas, Brenner, Malcolm K

Journal:

Cancer Gene Therapy

Year:

2001

Language:

english

File:

PDF, 326 KB

english, 2001

39

A strategy for treatment of Epstein–Barr virus-positive Hodgkin's disease by targeting interleukin 12 to the tumor environment using tumor antigen-specific T cells

Wagner, Hans-Joachim, Bollard, Catherine M, Vigouroux, Stéphane, Huls, M Helen, Anderson, Robert, Prentice, H Grant, Brenner, Malcolm K, Heslop, Helen E, Rooney, Cliona M

Journal:

Cancer Gene Therapy

Year:

2003

Language:

english

File:

PDF, 251 KB

english, 2003

40

E1A-induced apoptosis does not prevent replication of adenoviruses with deletion of E1b in majority of infected cancer cells

Thompson, Timothy C, Brenner, Malcolm K, McMasters, Kelly M, Zhou, Heshan Sam, Rao, Xiao-Mei, Tseng, Michael T, Zheng, Xinyu, Dong, Yanbin, Jamshidi-Parsian, Azemat

Journal:

Cancer Gene Therapy

Year:

2004

Language:

english

File:

PDF, 323 KB

english, 2004

41

Gene-Marked Autologous Hematopoietic Stem Cell Transplantation of Autoimmune Disease

Richard K. Burt, Malcolm Brenner, William Burns, Eva Courier, Gary Firestein, Bevra Hahn, Helen Heslop, Charles Link, Henry Mcfarland, Martin Roland, Mary Territo, George Tsokos, Ann Traynor

Journal:

Journal of Clinical Immunology

Year:

2000

Language:

english

File:

PDF, 54 KB

english, 2000

42

Aggressive peripheral CD70-positive t-cell lymphoma associated with severe chronic active EBV infection

Donald R. Shaffer, Andrea M. Sheehan, Zhongzhen Yi, Cheryl C. Rodgers, Catherine M. Bollard, Malcolm K. Brenner, Cliona M. Rooney, Helen E. Heslop, Stephen Gottschalk

Journal:

Pediatric Blood & Cancer

Year:

2012

Language:

english

File:

PDF, 299 KB

english, 2012

43

The contribution of marker gene studies to hemopoietic stem cell therapies

Malcolm K. Brenner

Journal:

Year:

1995

Language:

english

File:

PDF, 798 KB

english, 1995

44

Gene-Marking studies of hematopoietic cells

Bollard, Catherine M., Heslop, Helen E., Brenner, Malcolm K.

Journal:

International Journal of Hematology

Year:

2001

Language:

english

File:

PDF, 99 KB

english, 2001

45

Measurement of cardiac output by automated single-breath technique, and comparison with thermodilution and Fick methods in patients with cardiac disease

Mark R. Zenger, Matthew Brenner, Malcolm Haruno, Donald Mahon, Archie F. Wilson

Journal:

The American Journal of Cardiology

Year:

1993

Language:

english

File:

PDF, 518 KB

english, 1993

46

T-cell depletion of allogeneic bone marrow prevents acceleration of graft-versus-host disease induced by exogenous interleukin 2

Miroslav Malkovský, Malcolm K. Brenner, Ruth Hunt, Sohaila Rastan, Caroline Dore, Sheila Brown, Margaret E. North, Geoffrey L. Asherson, H.Grant Prentice, Peter B. Medawar

Journal:

Cellular Immunology

Year:

1986

Language:

english

File:

PDF, 360 KB

english, 1986

47

Cell-specific transmembrane injection of molecular cargo with gold nanoparticle-generated transient plasmonic nanobubbles

Ekaterina Y. Lukianova-Hleb, Daniel S. Wagner, Malcolm K. Brenner, Dmitri O. Lapotko

Journal:

Year:

2012

Language:

english

File:

PDF, 1.18 MB

english, 2012

48

Autoimmune disease induced by dendritic cell immunization against leukemia

Marie A. Roskrow, Dagmar Dilloo, Nobuhiro Suzuki, Wanyung Zhong, Cliona M. Rooney, Malcolm K. Brenner

Journal:

Leukemia Research

Year:

1999

Language:

english

File:

PDF, 285 KB

english, 1999

49

Adenovector-induced expression of human-CD40-ligand (hCD40L) by multiple myeloma cells: A model for immunotherapy

Gianpietro Dotti, Barbara Savoldo, Satoshi Takahashi, Tatiana Goltsova, Michael Brown, Donna Rill, Cliona Rooney, Malcolm Brenner

Journal:

Experimental Hematology

Year:

2001

Language:

english

File:

PDF, 194 KB

english, 2001

50

“The End of the Beginning”: Molecular and Cellular Biology of Gene Therapy: Keystone, 14–20 January 1999

Malcolm K. Brenner

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

1999

Language:

english

File:

PDF, 143 KB

english, 1999